Nautic Peptide Library

The peptide in skincare labels

GHK-Cu (copper peptide)

A three-amino-acid peptide found naturally in human blood, which holds tightly onto copper.

Size
3 amino acids (a tripeptide)
Made of
Glycine, histidine and lysine, plus copper
Discovered
1973
On labels as
Copper Tripeptide-1

The story

In 1973, scientist Loren Pickart was studying why blood from younger people seemed to affect liver tissue differently in the lab. He tracked the effect down to a tiny peptide made of just three amino acids: glycine, histidine and lysine, or GHK for short.

GHK turned out to have a very strong attraction to copper. When it holds a copper ion, it's called GHK-Cu.

Good to know

Today, GHK-Cu is best known as a skincare ingredient. On ingredient lists it appears as "Copper Tripeptide-1", and you'll find it in serums and creams in Australia, often with a blue tint from the copper.

In Australia, a peptide product counts as a cosmetic or a therapeutic good depending on how it's used and what's claimed about it. The TGA explains the difference.

Did you know?

The copper in GHK-Cu is what gives many copper peptide serums their distinctive blue colour.